| 2021-08-13 18:15:00August 13, 2021 |   Bentleigh Greens SC vs Eastern Lions SC | 18:15:006:15 pm | U21 NPL VIC | 2021 | Kingston Heath Soccer Complex |
| 2021-08-13 20:30:00August 13, 2021 | Bentleigh Greens SC vs Eastern Lions SC | 20:30:008:30 pm | NPL VIC Men | 2021 | Kingston Heath Soccer Complex |
| 2021-08-20 20:30:14August 20, 2021 |  Dandenong City SC vs Eastern Lions SC | 20:30:148:30 pm | NPL VIC Men | 2021 | Frank Holohan Soccer Complex |
| 2021-08-28 15:00:24August 28, 2021 |  Eastern Lions SC vs Melbourne Knights FC | 15:00:243:00 pm | NPL VIC Men | 2021 | |
| 2021-09-05 12:30:00September 5, 2021 |  Eastern Lions SC vs South Melbourne FC | 12:30:0012:30 pm | U21 NPL VIC | 2021 | Gardiners Creek Reserve |
| 2021-09-05 15:00:00September 5, 2021 | Eastern Lions SC vs South Melbourne FC | 15:00:003:00 pm | NPL VIC Men | 2021 | Gardiners Creek Reserve |
| 2021-09-12 12:30:00September 12, 2021 |  Eastern Lions SC vs Port Melbourne Sharks SC | 12:30:0012:30 pm | U21 NPL VIC | 2021 | Gardiners Creek Reserve |
| 2021-09-12 15:00:00September 12, 2021 | Eastern Lions SC vs Port Melbourne Sharks SC | 15:00:003:00 pm | NPL VIC Men | 2021 | Gardiners Creek Reserve |
| 2022-05-21 12:15:00May 21, 2022 |  Eastern Lions SC vs Dandenong Thunder FC | 12:15:0012:15 pm | U21 NPL VIC | 2022 | Gardiners Creek Reserve - Pitch 1 - (NPL) |
| 2022-05-21 15:00:00May 21, 2022 | Eastern Lions SC vs Dandenong Thunder FC | 15:00:003:00 pm | NPL VIC Men | 2022 | Gardiners Creek Reserve - Pitch 1 - (NPL) |
| 2022-05-27 18:15:00May 27, 2022 |  Oakleigh Cannons FC vs Eastern Lions SC | 18:15:006:15 pm | U21 NPL VIC | 2022 | Jack Edwards Reserve - Pitch 2 (S) |
| 2022-05-27 20:30:00May 27, 2022 | Oakleigh Cannons FC vs Eastern Lions SC | 20:30:008:30 pm | NPL VIC Men | 2022 | Jack Edwards Reserve - (NPL) |
| 2022-06-04 12:15:00June 4, 2022 |  Eastern Lions SC vs Altona Magic SC | 12:15:0012:15 pm | U21 NPL VIC | 2022 | TBC |
| 2022-06-04 15:00:00June 4, 2022 | Eastern Lions SC vs Altona Magic SC | 15:00:003:00 pm | NPL VIC Men | 2022 | TBC |
| 2022-06-11 17:30:00June 11, 2022 | Port Melbourne Sharks SC vs Eastern Lions SC | 17:30:005:30 pm | NPL VIC Men | 2022 | JL Murphy Reserve - SS Anderson Oval - Pitch 1 - (NPL) |
| 2022-06-11 19:30:00June 11, 2022 | Port Melbourne Sharks SC vs Eastern Lions SC | 19:30:007:30 pm | U21 NPL VIC | 2022 | JL Murphy Reserve - SS Anderson Oval - Pitch 1 - (NPL) |
| 2022-06-18 12:15:00June 18, 2022 | Eastern Lions SC vs Dandenong City SC | 12:15:0012:15 pm | U21 NPL VIC | 2022 | Gardiners Creek Reserve - Pitch 1 - (NPL) |
| 2022-06-18 15:00:00June 18, 2022 | Eastern Lions SC vs Dandenong City SC | 15:00:003:00 pm | NPL VIC Men | 2022 | Gardiners Creek Reserve - Pitch 1 - (NPL) |
| 2022-06-25 12:15:00June 25, 2022 |  Avondale FC vs Eastern Lions SC | 12:15:0012:15 pm | U21 NPL VIC | 2022 | Avenger Park |
| 2022-06-25 15:15:00June 25, 2022 | Avondale FC vs Eastern Lions SC | 15:15:003:15 pm | NPL VIC Men | 2022 | Avenger Park |
| 2022-07-02 12:15:00July 2, 2022 | Eastern Lions SC vs South Melbourne FC | 12:15:0012:15 pm | U21 NPL VIC | 2022 | Gardiners Creek Reserve - Pitch 1 - (NPL) |
| 2022-07-02 15:00:00July 2, 2022 | Eastern Lions SC vs South Melbourne FC | 15:00:003:00 pm | NPL VIC Men | 2022 | Gardiners Creek Reserve - Pitch 1 - (NPL) |
| 2022-07-08 18:30:00July 8, 2022 | Bentleigh Greens SC vs Eastern Lions SC | 18:30:006:30 pm | U21 NPL VIC | 2022 | Kingston Heath Soccer Complex - Pitch 2 (S) |
| 2022-07-08 20:30:00July 8, 2022 | Bentleigh Greens SC vs Eastern Lions SC | 20:30:008:30 pm | NPL VIC Men | 2022 | Kingston Heath Soccer Complex - Pitch 1 |
| 2022-07-16 12:15:00July 16, 2022 | Eastern Lions SC vs Melbourne Knights FC | 12:15:0012:15 pm | U21 NPL VIC | 2022 | Gardiners Creek Reserve - Pitch 1 - (NPL) |
| 2022-07-16 15:00:00July 16, 2022 | Eastern Lions SC vs Melbourne Knights FC | 15:00:003:00 pm | NPL VIC Men | 2022 | Gardiners Creek Reserve - Pitch 1 - (NPL) |
| 2022-07-24 12:30:00July 24, 2022 |  St Albans Saints SC vs Eastern Lions SC | 12:30:0012:30 pm | U21 NPL VIC | 2022 | Churchill Reserve - Pitch 1 - (NPL) |
| 2022-07-24 15:00:00July 24, 2022 | St Albans Saints SC vs Eastern Lions SC | 15:00:003:00 pm | NPL VIC Men | 2022 | Churchill Reserve - Pitch 1 - (NPL) |
