| 2021-02-28 17:00:00February 28, 2021 |   St Albans Saints SC vs Green Gully SC | 0 - 2 | Churchill Reserve |
| 2021-03-05 20:00:00March 5, 2021 |  Green Gully SC vs Hume City FC | 1 - 1 | Green Gully Reserve |
| 2021-03-13 15:15:00March 13, 2021 |  Avondale FC vs Green Gully SC | 0 - 2 | Avenger Park |
| 2021-03-19 20:00:00March 19, 2021 |  Green Gully SC vs Heidelberg United FC | 1 - 2 | Green Gully Reserve |
| 2021-03-26 20:30:00March 26, 2021 |  Oakleigh Cannons FC vs Green Gully SC | 2 - 0 | Jack Edwards Reserve |
| 2021-03-31 19:30:00March 31, 2021 |  Altona Magic SC vs Green Gully SC | 0 - 1 | Paisley Park Soccer Complex |
| 2021-04-09 20:00:00April 9, 2021 |  Green Gully SC vs South Melbourne FC | 0 - 1 | Green Gully Reserve |
| 2021-04-16 20:30:00April 16, 2021 |  Dandenong City SC vs Green Gully SC | 1 - 1 | Frank Holohan Soccer Complex |
| 2021-04-23 20:00:00April 23, 2021 |  Green Gully SC vs Melbourne Knights FC | 2 - 2 | Green Gully Reserve |
| 2021-05-01 17:05:00May 1, 2021 |  Bentleigh Greens SC vs Green Gully SC | 3 - 2 | Kingston Heath Soccer Complex |
| 2021-05-07 20:00:00May 7, 2021 |  Green Gully SC vs Eastern Lions SC | 3 - 2 | Green Gully Reserve |
| 2021-05-14 19:45:00May 14, 2021 |  Port Melbourne Sharks SC vs Green Gully SC | 2 - 0 | JL Murphy Reserve |
| 2021-05-21 20:00:00May 21, 2021 |  Green Gully SC vs Dandenong Thunder FC | 2 - 2 | Green Gully Reserve |
| 2021-06-20 15:00:00June 20, 2021 | Heidelberg United FC vs Green Gully SC | 1 - 0 | Olympic Village |
| 2021-06-25 20:00:00June 25, 2021 | Green Gully SC vs Oakleigh Cannons FC | 1 - 3 | Green Gully Reserve |
| 2021-07-02 20:00:00July 2, 2021 | Green Gully SC vs Altona Magic SC | 4 - 0 | Green Gully Reserve |
| 2021-07-09 19:30:00July 9, 2021 | South Melbourne FC vs Green Gully SC | 1 - 1 | Lakeside Stadium |
| 2021-07-16 20:00:00July 16, 2021 | Green Gully SC vs Dandenong City SC | 20:00:008:00 pm | Green Gully Reserve |
| 2021-07-23 19:30:00July 23, 2021 | Melbourne Knights FC vs Green Gully SC | 19:30:007:30 pm | Knights Stadium |
| 2021-07-30 20:00:00July 30, 2021 | Green Gully SC vs Bentleigh Greens SC | 0 - 2 | Green Gully Reserve |
| 2021-08-08 15:00:00August 8, 2021 | Eastern Lions SC vs Green Gully SC | 15:00:003:00 pm | Gardiners Creek Reserve |
| 2021-08-13 20:00:00August 13, 2021 | Green Gully SC vs St Albans Saints SC | 20:00:008:00 pm | Green Gully Reserve |
| 2021-08-20 20:00:28August 20, 2021 | Green Gully SC vs Port Melbourne Sharks SC | 20:00:288:00 pm | Green Gully Reserve |
| 2021-08-29 15:00:35August 29, 2021 | Dandenong Thunder FC vs Green Gully SC | 15:00:353:00 pm | George Andrews Reserve |
| 2021-09-04 17:30:00September 4, 2021 | Hume City FC vs Green Gully SC | 17:30:005:30 pm | ABD Stadium |
| 2021-09-12 15:00:00September 12, 2021 | Green Gully SC vs Avondale FC | 15:00:003:00 pm | Green Gully Reserve |
