| 2022-02-18 20:30:00February 18, 2022 |   Oakleigh Cannons FC vs Green Gully SC | 2 - 3 | NPL VIC Men | Jack Edwards Reserve - (NPL) |
| 2022-02-25 20:00:00February 25, 2022 |  Green Gully SC vs Altona Magic SC | 1 - 0 | NPL VIC Men | Green Gully Reserve - Pitch 1 - (NPL) |
| 2022-03-05 17:30:00March 5, 2022 |  Port Melbourne Sharks SC vs Green Gully SC | 2 - 0 | NPL VIC Men | JL Murphy Reserve - SS Anderson Oval - Pitch 1 - (NPL) |
| 2022-03-11 20:00:00March 11, 2022 |  Green Gully SC vs Dandenong City SC | 1 - 0 | NPL VIC Men | Green Gully Reserve - Pitch 1 - (NPL) |
| 2022-03-19 15:15:00March 19, 2022 |  Avondale FC vs Green Gully SC | 1 - 0 | NPL VIC Men | Avenger Park |
| 2022-03-26 15:45:00March 26, 2022 |  Green Gully SC vs South Melbourne FC | 0 - 2 | NPL VIC Men | Ballarat Regional Soccer Facility - Pitch 1 |
| 2022-04-01 20:30:00April 1, 2022 |  Bentleigh Greens SC vs Green Gully SC | 3 - 0 | NPL VIC Men | Kingston Heath Soccer Complex - Pitch 1 |
| 2022-04-08 20:00:00April 8, 2022 |  Green Gully SC vs Melbourne Knights FC | 2 - 1 | NPL VIC Men | Green Gully Reserve - Pitch 1 - (NPL) |
| 2022-04-16 15:00:00April 16, 2022 |  St Albans Saints SC vs Green Gully SC | 1 - 1 | NPL VIC Men | TBC |
| 2022-04-22 20:00:00April 22, 2022 |  Green Gully SC vs Hume City FC | 1 - 0 | NPL VIC Men | Green Gully Reserve - Pitch 1 - (NPL) |
| 2022-04-29 20:00:00April 29, 2022 |  Green Gully SC vs Heidelberg United FC | 4 - 0 | NPL VIC Men | Green Gully Reserve - Pitch 1 - (NPL) |
| 2022-05-07 15:00:00May 7, 2022 |  Eastern Lions SC vs Green Gully SC | 0 - 4 | NPL VIC Men | Gardiners Creek Reserve - Pitch 1 - (NPL) |
| 2022-05-13 20:00:00May 13, 2022 |  Green Gully SC vs Dandenong Thunder FC | 3 - 0 | NPL VIC Men | Green Gully Reserve - Pitch 1 - (NPL) |
| 2022-05-20 20:00:00May 20, 2022 | Green Gully SC vs Oakleigh Cannons FC | 20:00:008:00 pm | NPL VIC Men | Green Gully Reserve - Pitch 1 - (NPL) |
| 2022-05-28 18:00:00May 28, 2022 | Altona Magic SC vs Green Gully SC | 18:00:006:00 pm | NPL VIC Men | Paisley Park - Pitch 1 - (NPL) |
| 2022-06-03 20:00:00June 3, 2022 | Green Gully SC vs Port Melbourne Sharks SC | 20:00:008:00 pm | NPL VIC Men | Green Gully Reserve - Pitch 1 - (NPL) |
| 2022-06-11 16:45:00June 11, 2022 | Dandenong City SC vs Green Gully SC | 16:45:004:45 pm | NPL VIC Men | Frank Holohan Soccer Complex - Pitch 1 - (NPL) |
| 2022-06-17 20:00:00June 17, 2022 | Green Gully SC vs Avondale FC | 20:00:008:00 pm | NPL VIC Men | Green Gully Reserve - Pitch 1 - (NPL) |
| 2022-06-24 19:30:00June 24, 2022 | South Melbourne FC vs Green Gully SC | 19:30:007:30 pm | NPL VIC Men | Lakeside Stadium |
| 2022-07-01 20:00:00July 1, 2022 | Green Gully SC vs Bentleigh Greens SC | 20:00:008:00 pm | NPL VIC Men | Green Gully Reserve - Pitch 1 - (NPL) |
| 2022-07-08 19:30:00July 8, 2022 | Melbourne Knights FC vs Green Gully SC | 19:30:007:30 pm | NPL VIC Men | Knights Stadium - Pitch 1 |
| 2022-07-15 20:00:00July 15, 2022 | Green Gully SC vs St Albans Saints SC | 20:00:008:00 pm | NPL VIC Men | Green Gully Reserve - Pitch 1 - (NPL) |
| 2022-07-23 19:00:00July 23, 2022 | Hume City FC vs Green Gully SC | 19:00:007:00 pm | NPL VIC Men | ABD Stadium Broadmeadows Valley Park - Pitch 1 (NPL) |
South Melbourne FC
Oakleigh Cannons FC
Green Gully SC
Port Melbourne Sharks SC
Avondale FC
Bentleigh Greens SC
Dandenong Thunder FC
Altona Magic SC
St Albans Saints SC
Heidelberg United FC
Melbourne Knights FC
Dandenong City SC
Hume City FC
Eastern Lions SC
